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Does Neupogen cause bone pain? The rates of bone pain vary between agents, and may be associated with higher doses such as those used for stem cell mobilization (eg, filgrastim 10 mcg/kg). Although the exact mechanism of this pain is not well understood, one potential mechanism is that histamine may cause bone marrow edema and result in pain.
How do you know if you have bone metastases? Bone metastases are sometimes found because they cause problems, but in some cases, they ' re found before you have any symptoms. Lab tests and imaging tests (like x-rays or bone scans) are often used to see if and/or how far the cancer has spread. These tests may show bone metastases.
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